Article
Assessment of PD-1 positive cells on initial and secondary resected tumor specimens of newly diagnosed glioblastoma and its implications on patient outcome.
Journal of neuro-oncology - 1 Jun 2017
Miyazaki Tsubasa, Ishikawa Eiichi, Matsuda Masahide, Akutsu Hiroyoshi, Osuka Satoru, Sakamoto Noriaki, Takano Shingo, Yamamoto Tetsuya, Tsuboi Koji, Matsumura Akira
Abstract excerpt
Glioblastoma (GBM) is the most common type of malignant brain tumor and has a very poor prognosis. Most patients relapse within 12 months despite aggressive treatment and patient outcome after recurrent is extremely worse. This study was designed to clarify the change of the molecular expression, including programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1), on the initial and secondary resected tumor...
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