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Why Cancer & Metabolism? Why now?

23 Jan 2013

Abstract excerpt

The identification of oncogenic driver mutations of many cancers by deep sequencing is validating the oncogene versus tumor suppressor paradigm of tumorigenesis. At the same time, there is a profound resurgence of interest in metabolism in the context of neoplasia, both at the whole-organism level with respect to the influence of caloric intake on cancer behavior, and at the cellular level, with respect to...

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PMID: 24280107
DOI: 10.1186/2049-3002-1-1

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