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Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients.

Scientific reports - 25 Apr 2017

Feng Chun-Yun, Huang Xiao-Qiong, Cheng Xue-Wen, Wu Rong-Han, Lu Fan, Jin Zi-Bing

Abstract excerpt

High myopia (HM) is a leading cause of mid-way blindness with a high heritability in East Asia. Although only a few disease genes have been reported, a small proportion of patients could be identified with genetic predispositions. In order to expand the mutation spectrum of the causative genes in Chinese adult population, we investigated three genes, SLC39A5, LEPREL1 and LRPAP1, in a cohort of 187 independent...

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Identifiers

PMID: 28442722
DOI: 10.1038/s41598-017-01285-3
PMCID: PMC5430800

Genes

LRPAP1

Variants

Provenance

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Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients.PMID 28442722Read ↗

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