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Variants in FLRT3 and SLC35E2B identified using exome sequencing in seven high myopia families from Central Europe.

Advances in medical sciences - 1 Mar 2021

Swierkowska Joanna, Karolak Justyna A, Gambin Tomasz, Rydzanicz Malgorzata, Frajdenberg Agata, Mrugacz Malgorzata, Podfigurna-Musielak Monika, Stankiewicz Pawel, Lupski James R, Gajecka Marzena

Abstract excerpt

PURPOSE: High myopia (HM) is an eye disorder with both environmental and genetic factors involved. Many genetic factors responsible for HM were recognized worldwide, but little is known about genetic variants underlying HM in Central Europe. Thus, the aim of this study was to identify rare sequence variants involved in HM in families from Central Europe to better understand the genetic basis of HM. MATERIALS AND...

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PMID: 33711669
DOI: 10.1016/j.advms.2021.02.005

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