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Article

Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F.

Infection and immunity - 1 Jul 2017

Spencer Brady L, Saad Jamil S, Shenoy Anukul T, Orihuela Carlos J, Nahm Moon H

Abstract excerpt

Streptococcus pneumoniae (pneumococcus) produces many capsule types that differ in their abilities to evade host immune recognition. To explain these serotype-dependent protective capacities, many studies have investigated capsular thickness or the interaction of the capsule with complement proteins, but the effects of small chemical modifications of the capsule on its function have not been studied. One small...

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Identifiers

PMID: 28438972
DOI: 10.1128/IAI.00132-17
PMCID: PMC5478959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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