Article
DNA Methylation program in normal and alcohol-induced thinning cortex.
Alcohol (Fayetteville, N.Y.) - 1 May 2017
Öztürk Nail Can, Resendiz Marisol, Öztürk Hakan, Zhou Feng C
Abstract excerpt
While cerebral underdevelopment is a hallmark of fetal alcohol spectrum disorders (FASD), the mechanism(s) guiding the broad cortical neurodevelopmental deficits are not clear. DNA methylation is known to regulate early development and tissue specification through gene regulation. Here, we examined DNA methylation in the onset of alcohol-induced cortical thinning in a mouse model of FASD. C57BL/6 (B6) mice were...
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