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Cellular DNA methylation program during neurulation and its alteration by alcohol exposure

31 May 2011

Abstract excerpt

BACKGROUND: Epigenetic changes are believed to be among the earliest key regulators for cell fate and embryonic development. To support this premise, it is important to understand whether or not systemic epigenetic changes coordinate with the progression of development. We have demonstrated that DNA methylation is programmed when neural stem cells differentiate (Zhou et al.,2011). Here, we analyzed the DNA...

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PMID: 21630420
DOI: 10.1002/bdra.20820

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