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Article

Preconception allergen sensitization can induce B10 cells in offspring: a potential main role for maternal IgG

16 Apr 2017

Abstract excerpt

BACKGROUND: The mechanisms through which allergies can be inhibited after preconception immunization with allergens are not fully understood. We aimed to evaluate whether maternal immunization can induce a regulatory B (B10) cell population in offspring in concert with allergy inhibition. METHODS: C57BL/6 females were or were not immunized with OVA and were mated with normal WT males. Their offspring were...

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PMID: 28428801
DOI: 10.1186/s13223-017-0195-8

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