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Vitamin C Prevents Offspring DNA Methylation Changes Associated with Maternal Smoking in Pregnancy

19 Apr 2017

Abstract excerpt

RATIONALE: Infants whose mothers smoked during pregnancy demonstrate lifelong decreases in pulmonary function. DNA methylation changes associated with maternal smoking during pregnancy have been described in placenta and cord blood at delivery, in fetal lung, and in buccal epithelium and blood during childhood. We demonstrated in a randomized clinical trial ( ClinicalTrials.gov identifier, NCT00632476) that...

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PMID: 28422514
DOI: 10.1164/rccm.201610-2141oc

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