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Article

Hematopoietic stem/progenitor cell differentiation towards myeloid lineage is modulated by LIGHT/LIGHT receptor signaling.

Journal of cellular physiology - 1 Feb 2018

Chen Weikai, Lv Xin, Liu Changlong, Chen Ruoping, Liu Jianhe, Dai Haiyan, Zou Gang-Ming

Abstract excerpt

The cytokine LT-related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells (LIGHT) is a member of the tumor necrosis factor (TNF) superfamily. It is expressed primarily on activated T lymphocytes, and detectable on monocytes, granulocytes, and immune dendritic cells. It mainly plays a role in immune regulation including T cell activation and dendritic cell...

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Identifiers

PMID: 28422285
DOI: 10.1002/jcp.25967

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Hematopoietic stem/progenitor cell differentiation towards myeloid lineage is modulated by LIGHT/LIGHT receptor signaling.PMID 28422285Read ↗

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Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction.Semantic proximity Read ↗

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