Article
Impact of Antiretroviral Treatment Containing Tenofovir Difumarate on the Telomere Length of Aviremic HIV-Infected Patients
18 Apr 2017
Abstract excerpt
OBJECTIVE: To evaluate the in vivo relevance of the inhibitory effect of tenofovir on telomerase activity observed in vitro. DESIGN: Cross-sectional study of HIV-infected patients with suppressed virological replication (HIV RNA <50 copies/mL for more than 1 year). METHODS: Telomere length in whole blood was measured by quantitative real-time polymerase chain reaction. We performed a multivariate analysis to...
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