Article
Genetic alterations in mesiodens as revealed by targeted next-generation sequencing and gene co-occurrence network analysis.
Oral diseases - 1 Oct 2017
Kim Y Y, Hwang J, Kim H-S, Kwon H J, Kim S, Lee J H, Lee J H
Abstract excerpt
OBJECTIVE: Mesiodens is the most common type of supernumerary tooth which includes a population prevalence of 0.15%-1.9%. Alongside evidence that the condition is heritable, mutations in single genes have been reported in few human supernumerary tooth cases. Gene sequencing methods in tradition way are time-consuming and labor-intensive, whereas next-generation sequencing and bioinformatics are cost-effective for...
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