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Article

Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy.

Clinical epigenetics - 1 Jan 2017

Houshmand-Oeregaard Azadeh, Hansen Ninna S, Hjort Line, Kelstrup Louise, Broholm Christa, Mathiesen Elisabeth R, Clausen Tine D, Damm Peter, Vaag Allan

Abstract excerpt

BACKGROUND: Offspring of women with diabetes in pregnancy are at increased risk of type 2 diabetes mellitus (T2DM), potentially mediated by epigenetic mechanisms. The adipokines leptin, adiponectin, and resistin (genes: LEP, ADIPOQ, RETN) play key roles in the pathophysiology of T2DM. We hypothesized that offspring exposed to maternal diabetes exhibit alterations in epigenetic regulation of subcutaneous adipose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 1

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Source

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Identifiers

PMID: 28413567
DOI: 10.1186/s13148-017-0338-2
PMCID: PMC5390345

Genes

ADIPOQ
RETN
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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