Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newborns

22 Jun 2016

Abstract excerpt

BACKGROUND: Children exposed to gestational diabetes mellitus (GDM) are at a higher risk of developing obesity and type 2 diabetes. This susceptibility might involve brown adipose tissue (BAT), which is suspected to protect against obesity. The objective of this study is to assess whether fetal exposure to maternal hyperglycemia is associated with DNA methylation variations in genes involved in BAT genesis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Gestational Diabetes Research and Management
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27340502
DOI: 10.1186/s13148-016-0239-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newbornsPMID 27340502Read ↗

Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gapsSemantic proximity Read ↗

Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseasesSemantic proximity Read ↗

DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspringSemantic proximity Read ↗

From Mother to Child: Epigenetic Signatures of Hyperglycemia and Obesity during PregnancySemantic proximity Read ↗

DNA methylation profiles in the blood of newborn term infants born to mothers with obesitySemantic proximity Read ↗

The role of maternal DNA methylation in pregnancies complicated by gestational diabetesSemantic proximity Read ↗

DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in PregnancySemantic proximity Read ↗

Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcomeSemantic proximity Read ↗

Maternal diabetes and obesity influence the fetal epigenome in a largely Hispanic population.Semantic proximity Read ↗

Gestational diabetes and maternal obesity are associated with epigenome-wide methylation changes in childrenSemantic proximity Read ↗

Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association studySemantic proximity Read ↗

Gene Expression and DNA Methylation of <i>PPARGC1A</i> in Muscle and Adipose Tissue From Adult Offspring of Women With Diabetes in PregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.