Article
Expression of MRP1 and ABCG2 is associated with adverse clinical outcomes of papillary thyroid carcinoma with a solid component.
Human pathology - 1 Sept 2017
Ohashi Ryuji, Kawahara Kiyoko, Namimatsu Shigeki, Okamura Ritsuko, Igarashi Takehito, Sugitani Iwao, Naito Zenya
Abstract excerpt
Solid variant of papillary thyroid carcinoma (PTC) is characterized by a solid component (SC) retaining classical cytological features of PTC. Despite some controversies, PTC with SC (PTCSC) cases have poor prognosis compared with well-differentiated PTC. We investigated if cancer stem cells (CSCs) may have a role in pathogenesis of PTCSC. PTCSC tumors (n=27) were histologically represented by a mixture of...
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