New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis.

doi:10.1371/journal.pone.0175569

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Article

New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis.

PloS one - 1 Jan 2017

Oberbach Andreas, Schlichting Nadine, Feder Stefan, Lehmann Stefanie, Kullnick Yvonne, Buschmann Tilo, Blumert Conny, Horn Friedemann, Neuhaus Jochen, Neujahr Ralph, Bagaev Erik, Hagl Christian, Pichlmaier Maximilian, Rodloff Arne Christian, Gräber Sandra, Kirsch Katharina, Sandri Marcus, Kumbhari Vivek, Behzadi Armirhossein, Behzadi Amirali, Correia Joao Carlos, Mohr Friedrich Wilhelm, Friedrich Maik

Abstract excerpt

AIMS: In infective endocarditis (IE), a severe inflammatory disease of the endocardium with an unchanged incidence and mortality rate over the past decades, only 1% of the cases have been described as polymicrobial infections based on microbiological approaches. The aim of this study was to identify potential biodiversity of bacterial species from infected native and prosthetic valves. Furthermore, we compared...

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PMID: 28410379
DOI: 10.1371/journal.pone.0175569
PMCID: PMC5391965

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