Article
Polymorphisms in CARS are associated with gastric cancer risk: a two-stage case-control study in the Chinese population.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Nov 2017
Tian Tian, Xiao Ling, Du Jiangbo, Zhu Xun, Gu Yayun, Qin Na, Yan Caiwang, Liu Li, Ma Hongxia, Jiang Yue, Chen Jiaping, Yu Hao, Dai Juncheng
Abstract excerpt
BACKGROUND: The cysteinyl transfer RNA synthetase gene (CARS) is located on chromosome band 11p15.5, which is an important tumor-suppressor gene region. Mutations in CARS have been identified in many kinds of cancers; however, evidence for a relationship between genetic variants in CARS and gastric cancer at the population level is still lacking. Thus, we explored the association of variants in CARS with gastric...
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