Article
Palmitoylation of proteins in cancer.
Biochemical Society transactions - 15 Apr 2017
Resh Marilyn D
Abstract excerpt
Post-translational modification of proteins by attachment of palmitate serves as a mechanism to regulate protein localization and function in both normal and malignant cells. Given the essential role that palmitoylation plays in cancer cell signaling, approaches that target palmitoylated proteins and palmitoyl acyltransferases (PATs) have the potential for therapeutic intervention in cancer. Highlighted here are...
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