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Article

The Importance of VEGF-KDR Signaling Pathway Genes should Not Be Ignored When the Risk of Developing Multiple Sclerosis is Taken into Consideration.

Journal of molecular neuroscience : MN - 1 May 2017

Mazdeh Mehrdokht, Noroozi Rezvan, Gharesouran Jalal, Sayad Arezou, Komaki Alireza, Eftekharian Mohammad Mahdi, Habibi Mohsen, Toghi Mehdi, Taheri Mohammad

Abstract excerpt

Vascular endothelial growth factor (VEGF) and its receptor kinase insert domain-containing receptor (KDR) pathway trigger the process of angiogenesis as well as inflammation, which contributes to the development and progression of demyelinating lesions in multiple sclerosis. This work is a case-control study comprising of a total of 400 subjects with multiple sclerosis and 400 healthy controls. Participants were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28401369
DOI: 10.1007/s12031-017-0912-2

Genes

KDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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