Article
Exploring single nucleotide polymorphisms previously related to obesity and metabolic traits in pediatric-onset type 2 diabetes.
Acta diabetologica - 1 Jul 2017
Miranda-Lora América Liliana, Cruz Miguel, Aguirre-Hernández Jesús, Molina-Díaz Mario, Gutiérrez Jorge, Flores-Huerta Samuel, Klünder-Klünder Miguel
Abstract excerpt
AIMS: To evaluate the association of 64 obesity-related polymorphisms with pediatric-onset type 2 diabetes and other glucose- and insulin-related traits in Mexican children. METHODS: Case-control and case-sibling designs were followed. We studied 99 patients with pediatric-onset type 2 diabetes, their siblings (n = 101) without diabetes, 83 unrelated pediatric controls and 137 adult controls. Genotypes were...
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