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Article

Subclinical atherosclerosis in rheumatoid arthritis is driven by MicroRNA polymorphisms and NETosis.

Arthritis research & therapy - 9 Feb 2026

Reguilón Laura, Gómez Jesús H, Carrillo-Tornel Salvador, Saiz Encarnación, Pina María F, Guzmán-Almansa Miriam, García-Barberá Nuria, Guijarro-Carrillo Pedro J, Hervés Ignacio, Plasencia Juana M, Herranz María T, Lozano María L, Pérez-Sánchez Carlos, López-Pedrera Chary, Martínez Constantino, González-Conejero Rocío

Abstract excerpt

BACKGROUND: Rheumatoid arthritis (RA) is associated with increased cardiovascular disease (CVD) risk, not fully explained by traditional risk factors. Neutrophil extracellular traps (NETs) and regulatory microRNA polymorphisms (miR-SNPs) may contribute to RA-related atherosclerosis through thromboinflammatory mechanisms. OBJECTIVES: To investigate whether miR-SNPs (rs2431697, rs3746444, rs11614913) are associated...

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Source

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Identifiers

PMID: 41656252
DOI: 10.1186/s13075-025-03727-0
PMCID: PMC12918252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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