Methodological issues limit interpretation of negative effects of satellite cell depletion on adult muscle hypertrophy

Abstract excerpt

We are writing regarding the recent publication in Development entitled ‘Satellite cell depletion prevents fiber hypertrophy in skeletal muscle’ (Egner et al., 2016). Egner et al. claim to have ‘essentially repeated’ our work (McCarthy et al., 2011); however, we think that methodological differences between the two studies make it impossible to compare the results directly. More importantly, technical problems...

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