Article
Relationship of lipoprotein lipase gene variants and fasting triglyceride levels in a pediatric population: The CASPIAN-III study.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Jan 2000
Kelishadi Roya, Hashemipour Mahin, Esteki Behnoosh, Tajadini Mohammad Hasan, Rafiei Laleh, Motlagh Mohammad Esmaeil, Vaseghi Golnaz, Ardalan Gelayol, Javanmard Shaghayegh Haghjooy
Abstract excerpt
BACKGROUND: Lipoprotein lipase (LPL) is one of the major enzymes responsible for the hydrolysis of triglyceride (TG)-rich lipoprotein. The effects of LPL polymorphisms on serum TG are inconsistent among different populations. OBJECTIVES: This study aims to assess the TG serum concentration and distributions of three LPL single nucleotide polymorphisms (SNPs), namely D9N, HINDIII and S447X, in a nationally...
Topics
- Adolescent
- Child
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hypertriglyceridemia
- Iran
- Lipoprotein Lipase
- Male
