Article
Role of 3 lipoprotein lipase variants in triglycerides in children receiving highly active antiretroviral therapy.
The Pediatric infectious disease journal - 1 Feb 2015
Colombero Cecilia, Catano Gabriel, Rocco Carlos A, Mecikovsky Débora, Bologna Rosa, Aulicino Paula C, Sen Luisa, Mangano Andrea
Abstract excerpt
BACKGROUND: Lipoprotein lipase is a key enzyme in lipid metabolism, especially for plasma triglycerides (TGs). Genetic variants have been associated with lipid levels in healthy individuals, cardiovascular disease, obesity and diabetes. Our aim was to evaluate the influence of 3 polymorphisms: Hind III, Pvu II and S447X in plasma TG levels in human immunodeficiency virus-1-infected children under highly active...
Topics
- Antiretroviral Therapy, Highly Active
- Argentina
- Blood Chemical Analysis
- Child, Preschool
- Female
- Gene Frequency
- Genotype
- HIV Infections
- Humans
- Infant
- Lipoprotein Lipase
- Male
- Polymerase Chain Reaction