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Article

Retrospective Analysis of Molecular and Immunohistochemical Characterization of 381 Primary Brain Tumors.

Journal of neuropathology and experimental neurology - 1 Mar 2017

Ballester Leomar Y, Fuller Gregory N, Powell Suzanne Z, Sulman Erik P, Patel Keyur P, Luthra Rajyalakshmi, Routbort Mark J

Abstract excerpt

The classification of brain tumors has traditionally depended on microscopic examination of hematoxylin and eosin-stained tissue sections. The increased understanding of clinically relevant genetic alterations has led to the incorporation of molecular signatures as part of the diagnosis of brain malignancies. Advances in sequencing technologies have facilitated the use of next-generation sequencing (NGS) assays...

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Identifiers

PMID: 28395087
DOI: 10.1093/jnen/nlw119

Genes

BRAF
CTNNB1
EGFR
IDH1
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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