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Article

A Zebrafish Model of Human Fibrodysplasia Ossificans Progressiva

10 Apr 2017

Abstract excerpt

Fibrodysplasia ossificans progressiva (FOP) is a rare, autosomal dominant genetic disorder in humans characterized by explosive inflammatory response to injury leading to gradual ossification within fibrous tissues, including skeletal muscle, tendons, and ligaments. A variety of animal models are needed to study and understand the etiology of human FOP. To address this need, here we present characterizations of...

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PMID: 28394244
DOI: 10.1089/zeb.2016.1398

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