Article
NY-ESO-1 expression predicts an aggressive phenotype of ovarian cancer.
Gynecologic oncology - 1 Jun 2017
Szender J Brian, Papanicolau-Sengos Antonios, Eng Kevin H, Miliotto Anthony J, Lugade Amit A, Gnjatic Sacha, Matsuzaki Junko, Morrison Carl D, Odunsi Kunle
Abstract excerpt
OBJECTIVES: NY-ESO-1 is a cancer testis antigen and a promising target for immunotherapy. The purpose of this study was to determine the expression frequency, immunogenicity, and clinical impact of NY-ESO-1 in ovarian cancer. METHODS: Immunohistochemistry (IHC), reverse-transcription polymerase chain reaction (RT-PCR), and quantitative-PCR (qRT-PCR) were utilized in an ovarian cancer (including Fallopian tube and...
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