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Article

Discovery of new muscarinic acetylcholine receptor antagonists from Scopolia tangutica.

Scientific reports - 7 Apr 2017

Du Nana, Liu Yanfang, Zhang Xiuli, Wang Jixia, Zhao Jianqiang, He Jian, Zhou Han, Mei Lijuan, Liang Xinmiao

Abstract excerpt

Scopolia tangutica (S. tangutica) is a traditional Chinese medicinal plant used for antispasmodics, anesthesia, analgesia and sedation. Its pharmacological activities are mostly associated with the antagonistic activity at muscarinic acetylcholine receptors (mAchRs) of several known alkaloids such as atropine and scopolamine. With our recent identification of four hydroxycinnamic acid amides from S. tangutica, we...

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PMID: 28387362
DOI: 10.1038/srep46067
PMCID: PMC5384254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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