Article
miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis.
Investigative ophthalmology & visual science - 1 Apr 2017
Yang Lu, Du Liping, Yue Yingying, Huang Yike, Zhou Qingyun, Cao Shuang, Qi Jian, Liang Liang, Wu Lili, Wang Chaokui, Ye Zi, Tian Yuan, Kijlstra Aize, Hou Shengping, Yang Peizeng
Abstract excerpt
Purpose: To investigate the association of microRNA (miRNA) copy number variants (CNVs) with acute anterior uveitis (AAU) with or without ankylosing spondylitis (AS) and to assess underlying disease mechanisms. Methods: This study included 768 patients with AAU+AS+ or AAU+AS- and 660 controls from a Chinese Han population. Genotyping of CNVs was performed by TaqMan PCR. The expression of miRNAs, transfection...
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