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Article

FoxO1 gene confers genetic predisposition to acute anterior uveitis with ankylosing spondylitis.

Investigative ophthalmology & visual science - 20 Nov 2014

Yu Hongsong, Liu Yunjia, Zhang Lijun, Wu Lili, Zheng Minming, Cheng Ling, Luo Le, Kijlstra Aize, Yang Peizeng

Abstract excerpt

PURPOSE: Recent studies have shown that a decrease of regulatory T (Treg) cells may contribute to the activity of acute anterior uveitis (AAU) and ankylosing spondylitis (AS). A number of immunogenetic factors including IL2RA, miR-27a, miR-182, and FoxO1 are associated with Treg cell function. In this study, we investigated the association between polymorphisms of these genes and AAU with or without AS in a...

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PMID: 25414190
DOI: 10.1167/iovs.14-15460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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