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Article

Intracellular localization of survivin determines biological behavior in colorectal cancer

23 Jul 2009

Abstract excerpt

Survivin is a bifunctional protein that suppresses apoptosis and regulates cell division and is highly expressed in various human cancers. Recently, the intracellular localization of survivin in tumors has been suggested as a prognostic marker, but the molecular mechanisms are not understood. The aims of the present study were to investigate the different localization of survivin expression in colorectal...

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PMID: 19639203
DOI: 10.3892/or_00000471

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