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Article

Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome.

Scientific reports - 4 Apr 2017

Lingappan Krithika, Maity Suman, Jiang Weiwu, Wang Lihua, Couroucli Xanthi, Veith Alex, Zhou Guodong, Coarfa Cristian, Moorthy Bhagavatula

Abstract excerpt

Hyperoxia contributes to lung injury in experimental animals and diseases such as acute respiratory distress syndrome in humans. Cytochrome P450 (CYP)1A enzymes are protective against hyperoxic lung injury (HLI). The molecular pathways and differences in gene expression that modulate these protective effects remain largely unknown. Our objective was to characterize genotype specific differences in the...

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Source

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Identifiers

PMID: 28377578
DOI: 10.1038/s41598-017-00516-x
PMCID: PMC5428698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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