Article
Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2017
Assadipour Yasmine, Zacharakis Nikolaos, Crystal Jessica S, Prickett Todd D, Gartner Jared J, Somerville Robert P T, Xu Hui, Black Mary A, Jia Li, Chinnasamy Harshini, Kriley Isaac, Lu Lily, Wunderlich John R, Zheng Zhili, Lu Yong-Chen, Robbins Paul F, Rosenberg Steven A, Goff Stephanie L, Feldman Steven A
Abstract excerpt
Purpose: The administration of autologous tumor-infiltrating lymphocytes (TILs) can mediate durable tumor regressions in patients with melanoma likely based on the recognition of immunogenic somatic mutations expressed by the cancer. There are limited data regarding the immunogenicity of mutations in breast cancer. We sought to identify immunogenic nonsynonymous mutations in a patient with triple-negative breast...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
