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Article

Impact of microRNA-375 and its target gene SMAD-7 polymorphism on susceptibility of colorectal cancer.

Journal of clinical laboratory analysis - 1 Jan 2018

Shaker Olfat Gamil, Mohammed Shereen Rashad, Mohammed Asmaa Mohammed, Mahmoud Zeinab

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) has a high morbidity and mortality. Many studies reported that mir-375 is frequently down-regulated in many cancers including esophageal cancer, hepatocellular carcinoma, breast cancer and leukemias. AIM: Our aim was to study the expression of microRNA-375 and its target gene SMAD-7 polymorphisms (rs4939827) in CRC patients in comparison to control subjects and to correlate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28374902
DOI: 10.1002/jcla.22215
PMCID: PMC6817095

Genes

SMAD7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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