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Article

Acute ethanol exposure-induced autophagy-mediated cardiac injury via activation of the ROS-JNK-Bcl-2 pathway.

Journal of cellular physiology - 1 Feb 2018

Zhu Zhongxin, Huang Yewei, Lv Lingchun, Tao Youli, Shao Minglong, Zhao Congcong, Xue Mei, Sun Jia, Niu Chao, Wang Yang, Kim Sunam, Cong Weitao, Mao Wei, Jin Litai

Abstract excerpt

Binge drinking is associated with increased cardiac autophagy, and often triggers heart injury. Given the essential role of autophagy in various cardiac diseases, this study was designed to investigate the role of autophagy in ethanol-induced cardiac injury and the underlying mechanism. Our study showed that ethanol exposure enhanced the levels of LC3-II and LC3-II positive puncta and promoted cardiomyocyte...

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Source

Identifiers

PMID: 28369910
DOI: 10.1002/jcp.25934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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