Article
Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy
16 May 2008
Abstract excerpt
A significant understanding of the genetic signaling pathways governing the extrinsic and intrinsic apoptotic pathways has been established. In recent years, the role of apoptosis in the heart during ischemic and non-ischemic cardiomyopathies has been under investigation and reported to contribute to ventricular remodeling and heart failure. Autophagy has been recently characterized as an essential cellular...
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