Polymorphisms of STS gene and SULT2A1 gene and neurosteroid levels in Han Chinese boys with attention-deficit/hyperactivity disorder: an exploratory investigation.

doi:10.1038/srep45595

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Polymorphisms of STS gene and SULT2A1 gene and neurosteroid levels in Han Chinese boys with attention-deficit/hyperactivity disorder: an exploratory investigation.

Scientific reports - 3 Apr 2017

Wang Liang-Jen, Chan Wen-Ching, Chou Miao-Chun, Chou Wen-Jiun, Lee Min-Jing, Lee Sheng-Yu, Lin Pao-Yen, Yang Yi-Hsin, Yen Cheng-Fang

Abstract excerpt

This study examined the relationships among polymorphisms of the STS gene and SULT2A1 gene, dehydroepiandrosterone (DHEA) and its sulfated form (DHEA-S), and characteristics of attention-deficit/hyperactivity disorder (ADHD). We used cheek swabs to obtain the genomic DNA of 200 ADHD male probands (mean age: 8.7 years), 192 patients' mothers and 157 patients' fathers. Three SNPs in the STS gene (rs6639786,...

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PMID: 28367959
DOI: 10.1038/srep45595
PMCID: PMC5377367

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