Article
Ion mobility-mass spectrometry analysis of serum N-linked glycans from esophageal adenocarcinoma phenotypes.
Journal of proteome research - 7 Dec 2012
Gaye M M, Valentine S J, Hu Y, Mirjankar N, Hammoud Z T, Mechref Y, Lavine B K, Clemmer D E
Abstract excerpt
Three disease phenotypes, Barrett's esophagus (BE), high-grade dysplasia (HGD), esophageal adenocarcinoma (EAC), and a set of normal control (NC) serum samples are examined using a combination of ion mobility spectrometry (IMS), mass spectrometry (MS), and principal component analysis (PCA) techniques. Samples from a total of 136 individuals were examined, including 7 characterized as BE, 12 as HGD, 56 as EAC,...
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