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Article

An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations.

Hemoglobin - 1 Nov 2016

Lee Helena H L, Mak Annisa S L, Kou K O, Poon C F, Wong W S, Chiu K H, Au Patrick K C, Chan Kelvin Y K, Kan Anita S Y, Tang Mary H Y, Leung K Y

Abstract excerpt

Hydrops fetalis is commonly due to Hb Bart's (γ4) disease in South East Asia. Here, we report an unusual case of hydrops fetalis due to congenital dyserythropoietic anemia (CDA) associated with compound heterozygosity for Krüppel-like factor 1 (KLF1) gene mutations. Fetal cardiomegaly was first detected on routine mid-trimester scan in a pregnant woman with normal mean corpuscular volume (MCV) and Rhesus positive...

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Source

Identifiers

PMID: 28361594
DOI: 10.1080/03630269.2016.1267017

Genes

KLF1
CDA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations.PMID 28361594Read ↗

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Congenital Nonspherocytic Hemolytic Anemia Caused by Krüppel-Like Factor 1 Gene Variants: Another Case Report.Semantic proximity Read ↗

Hemoglobin Bart’s hydrops fetalis: charting the past and envisioning the futureSemantic proximity Read ↗

Hydrops Fetalis Caused by α-Thalassemia: An Emerging Health Care ProblemSemantic proximity Read ↗

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Compound Heterozygosity for KLF1 Mutations Causing Hemolytic Anemia in Children: A Case Report and Literature ReviewSemantic proximity Read ↗

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