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Article

Loss of E-cadherin as Part of a Migratory Phenotype in Melanoma Is Associated With Ulceration.

The American Journal of dermatopathology - 1 Sept 2017

Bønnelykke-Behrndtz Marie L, Steiniche Torben, Nørgaard Peter, Danielsen Allan V, Damsgaard Tine E, Christensen Ib J, Bastholt Lars, Møller Holger J, Schmidt Henrik

Abstract excerpt

It has been suggested that embryogenic properties of migratory cells are reactivated during wound healing and metastasis in adults. This might explain the association between wound-induced inflammation and poor survival in patients with ulcerated melanoma. Linking inflammation with a migratory phenotype, we characterize the infiltration of innate inflammatory cells, loss of cell-to-cell adhesion (E-cadherin),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28350549
DOI: 10.1097/DAD.0000000000000750

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