Article
Phase variable DNA repeats in Neisseria gonorrhoeae influence transcription, translation, and protein sequence variation.
Microbial genomics - 1 Aug 2016
Zelewska Marta A, Pulijala Madhuri, Spencer-Smith Russell, Mahmood Hiba-Tun-Noor A, Norman Billie, Churchward Colin P, Calder Alan, Snyder Lori A S
Abstract excerpt
There are many types of repeated DNA sequences in the genomes of the species of the genus Neisseria, from homopolymeric tracts to tandem repeats of hundreds of bases. Some of these have roles in the phase-variable expression of genes. When a repeat mediates phase variation, reversible switching between tract lengths occurs, which in the species of the genus Neisseria most often causes the gene to switch between...
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