Article
Whole-genome sequencing of a quarter-century melioidosis outbreak in temperate Australia uncovers a region of low-prevalence endemicity.
Microbial genomics - 1 Jul 2016
Chapple Stephanie N J, Sarovich Derek S, Holden Matthew T G, Peacock Sharon J, Buller Nicky, Golledge Clayton, Mayo Mark, Currie Bart J, Price Erin P
Abstract excerpt
Melioidosis, caused by the highly recombinogenic bacterium Burkholderia pseudomallei, is a disease with high mortality. Tracing the origin of melioidosis outbreaks and understanding how the bacterium spreads and persists in the environment are essential to protecting public and veterinary health and reducing mortality associated with outbreaks. We used whole-genome sequencing to compare isolates from a historical...
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