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Proteasome expression and activity in cancer and cancer stem cells

1 Mar 2017

Abstract excerpt

Proteasome is a multi-protein organelle that participates in cellular proteostasis by destroying damaged or short-lived proteins in an organized manner guided by the ubiquitination signal. By being in a central place in the cellular protein complement homeostasis, proteasome is involved in virtually all cell processes including decisions on cell survival or death, cell cycle, and differentiation. These processes...

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PMID: 28345458
DOI: 10.1177/1010428317692248

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