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DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

24 Mar 2017

Abstract excerpt

BACKGROUND: The association of in vitro fertilisation (IVF) and DNA methylation has been studied predominantly at regulatory regions of imprinted genes and at just thousands of the ~28 million CpG sites in the human genome. METHODS: We investigated the links between IVF and DNA methylation patterns in whole cord blood cells (n = 98) and cord blood mononuclear cells (n = 82) from newborn twins using genome-wide...

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Share to Assisted Reproductive Technology and Twin Pregnancy
Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28340599
DOI: 10.1186/s13073-017-0413-5

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