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Article

Nutrient sensing by absorptive and secretory progenies of small intestinal stem cells.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jun 2017

Kishida Kunihiro, Pearce Sarah C, Yu Shiyan, Gao Nan, Ferraris Ronaldo P

Abstract excerpt

Nutrient sensing triggers responses by the gut-brain axis modulating hormone release, feeding behavior and metabolism that become dysregulated in metabolic syndrome and some cancers. Except for absorptive enterocytes and secretory enteroendocrine cells, the ability of many intestinal cell types to sense nutrients is still unknown; hence we hypothesized that progenitor stem cells (intestinal stem cells, ISC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28336548
DOI: 10.1152/ajpgi.00416.2016
PMCID: PMC5495913

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