Article
Nine differentially expressed genes from a post mortem study and their association with suicidal status in a sample of suicide completers, attempters and controls.
Journal of psychiatric research - 1 Aug 2017
Balestri Martina, Crisafulli Concetta, Donato Luigi, Giegling Ina, Calati Raffaella, Antypa Niki, Schneider Barbara, Marusic Dragan, Tarozzi Maria Eugenia, Marusic Dorjan, Paragi Metka, Hartmann Annette M, Konte Bettina, Marsano Agnese, Serretti Alessandro, Rujescu Dan
Abstract excerpt
Several lines of evidence indicate that suicidal behaviour is partly heritable, with multiple genes implicated in its aetiology. We focused on nine genes (S100A13, EFEMP1, PCDHB5, PDGFRB, CDCA7L, SCN2B, PTPRR, MLC1 and ZFP36) which we previously detected as differentially expressed in the cortex of suicide victims compared to controls. We investigated 84 variants within these genes in 495 suicidal subjects (299...
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