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Article

Combinations of Avibactam and Carbapenems Exhibit Enhanced Potencies Against Drug-Resistant Mycobacterium Abscessus

16 Feb 2017

Abstract excerpt

AIM: The objective of this study was to assess if avibactam, a new β-lactamase inhibitor, can restore the potency of carbapenems, a sub-class of β-lactams, against Mycobacterium abscessus clinical isolates. MATERIALS & METHODS: 28 M. abscessus clinical isolates that are resistant to multiple drugs currently used to treat its infection were included. MIC of carbapenems alone and in combination with avibactam...

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PMID: 28326811
DOI: 10.2217/fmb-2016-0234

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