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The use of dual β-lactams to restore susceptibility of Mycobacterium avium complex

3 Sept 2024

Abstract excerpt

Abstract Background The Mycobacterium avium complex (MAC) are non-tuberculous mycobacteria responsible for chronic and debilitating conditions. Guideline-recommended therapy for MAC is a combination of clarithromycin/azithromycin, ethambutol and a rifamycin. However, culture conversion rates with this regimen are 67%. Alternative treatment options are needed. Recent findings of β-lactam combinations in the...

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PMID: 39281290
DOI: 10.1093/jacamr/dlae142

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