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Article

Association between 16S rRNA gene mutations and susceptibility to amikacin in Mycobacterium avium Complex and Mycobacterium abscessus clinical isolates.

Scientific reports - 17 Mar 2021

Kim Su-Young, Kim Dae Hun, Moon Seong Mi, Song Ju Yeun, Huh Hee Jae, Lee Nam Yong, Shin Sung Jae, Koh Won-Jung, Jhun Byung Woo

Abstract excerpt

We evaluated the association between 16S rRNA gene (rrs) mutations and susceptibility in clinical isolates of amikacin-resistant nontuberculous mycobacteria (NTM) in NTM-pulmonary disease (PD) patients. Susceptibility was retested for 134 amikacin-resistant isolates (minimum inhibitory concentration [MIC] ≥ 64 µg/ml) from 86 patients. Amikacin resistance was reconfirmed in 102 NTM isolates from 62 patients with...

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Identifiers

PMID: 33731862
DOI: 10.1038/s41598-021-85721-5
PMCID: PMC7969740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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