Article
Quantitative Proteome Heterogeneity in Myeloproliferative Neoplasm Subtypes and Association with JAK2 Mutation Status.
Molecular cancer research : MCR - 1 Jul 2017
Socoro-Yuste Nuria, Čokić Vladan P, Mondet Julie, Plo Isabelle, Mossuz Pascal
Abstract excerpt
Apart from well-known genetic abnormalities, several studies have reported variations in protein expression in Philadelphia-negative myeloproliferative neoplasm (MPN) patients that could contribute toward their clinical phenotype. In this context, a quantitative mass spectrometry proteomics protocol was used to identify differences in the granulocyte proteome with the goal to characterize the pathogenic role of...
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